When Blade(Wesley Snipes)'s mother was bitten by a vampire during pregnancy, she did not know that she gave her son a special gift while dying: All the good vampire attributes in combination with the best human skills. Blade grew up to be a vampire hunter for revenge on his mother's death. He is helped in his mission by his life-long friend Whistler(Kris Kristofferson). With the addition of a new ally, Dr. Karen Jenson(N'Bushe Wright), Blade endeavors to prevent the evil Frost from unleashing the blood god upon the world. The vampires, who managed to infiltrate nearly every major organization, need Blade's very special blood to summon La Magra, the blood god, in order to reign over the human cattle, as they call us.