After his court testimony puts a key mafia figure into San Quentin, Inspector Dirty Harry Callahan finds unwanted fame. Now it seems that every hired killer in town is after him. To make it worse, Homicide wants him to go public: Play nice with the press and work with new partner Al Quan. British horror film director Peter Swan, who is in town to film a video for drug-addicted rock star Johnny Squares, plays a game with his crew known as "The Dead Pool", where they each choose a set of 10 celebrities who they think will die before the game ends. The winner of the game is the one with most number of dead celebrities on their list. And the problems start when the people on Peter's list start to die under mysterious circumstances. Following the death of Johnny Squares, DirtyHarry learns of The Dead Pool. And Dirty Harry discovers that his own name is on the list. All fingers seem to point to Peter, mainly since the celebrities that are dying are the same as those on his list. Dirty Harry also has to contend with TV reporter Samantha Walker, who'd just love to do a big story on him, and her name is also on the list. DirtyHarry races to unmask the killer before Dirty Harry himself winds up on the losing end of this game.