The body of Agent Strahm is completely smashed and destroyed and Detective Mark Hoffman frames him. Strahm is accused of being Jigsaw's apprentice and the FBI chases him. Dan Erickson calls Hoffman and he learns that Agent Lindsey Perez has not died. When Dan finds a tape with the voice of the killer, he invites Hoffman and Perez to go with him to the laboratory to see the progress with the identification of the real voice. John's widow Jill Tuck receives a box from his lawyer with six envelops with instructions and she gives the first five to Hoffman. The unethical CEO of the Umbrella Health, William Easton, and his team are abducted and William is forced to play a game and choose who will live or die to save his family and him.