Four boys grew up as inseparable buddies. Billy Newwood's untimely death and funeral brings them together in a nostalgic mood. Harmless hedonistic jailbird Tom Marshall easily convinces Jerry Conlaine, now a bored and eternally business accountant, and with his help 'outvotes' Dan Mott, a dentist with numerous phobias, it's time to make true an old blood oath. They set out by canoe to make the adventurous journey down the Columbia River which Tommy must have been planning, searching for the treasure of long missing airliner hijacker D.B. Cooper. The mix of belated coming of age and early midlife crisis turns out more adventurous then anyone bargained for: besieged by a grizzly, the elements, a forest-hidden marijuana farming gang and their own frustrations.