Rich but sick millionnarie Edwina Cutwater feels her untimely death coming up. She never could enjoy life, as she was either in a wheelchair or in bed, so she decided to take a chance: Prahka Lasa, a Tibetan master of meditation, should transfer her soul into the body of Terry Hoskins, whose soul therefore will become one with the universe. Accidentally, her soul is transferred into the body of her unliked lawyer Roger Cobb, whose soul remains in his body. Now, Edwina has control about the right half of Roger's body, his soul about only the left half. They struggle together to get her soul into the right body, but not without having some conflicts between themselves to solve.